Our researchers are elucidating molecular and cellular basis of hematological disorders
Mohandas Narla
Distinguished Scientist, Head, Laboratory of Red Cell Physiology
• Research has contributed to an improved understanding of the molecular and structural basis for red cell membrane disorders and abnormalities
• Pioneer in developing novel techniques to study the development of red blood cells from stem cells
Xiuli An
Head, Laboratory of Membrane Biology
• Studies to understand how red cells are produced in the bone marrow and the molecular basis of red cell disorders
• Research to improve ex vivo red cell production from stem cells
Bruce Sachais, MD, PhD
Senior Vice President, Enterprise Chief Medical Officer and Head of Translational Research and Development Laboratory
• Research on platelets disorders and platelet molecules causing disease
• Studies on improving diagnosis and developing novel treatments for heparin induced thrombocytopenia/thrombosis (HITT)
Patricia Shi, MD
Medical Director Head, Clinical Research in Sickle Cell Disease
• Initiated clinical studies for several new therapies for sickle cell disease to treat pain crisis and prevent organ failure as well as new protocols for mobilization of hematopoietic stem cells currently used for all gene therapy trials in sickle cell disease
• Research in improving techniques and processes for collection of cellular therapy products
Francesca Vinchi, PhD
Head, Laboratory of Iron Research
• Studies on iron overload disorders and iron deficiency anemia
• Research on novel drugs for removing excess iron to reduce the risk of liver cirrhosis, and heart failure
Hui Zhong, PhD
Head, Laboratory of Immune Regulation
• Studies on mechanisms abnormal immune functions in blood disorders
• Research on therapies targeting immune subsets called monocytes in inflammatory disease and development of monocyte diagnostics to identify at risk patients
